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Shastri, J. S.
- Adult Worms of Trichuris trichiura in an Anaemic Adult Patient
Authors
1 Department of Microbiology, Topiwala National Medical College & B.Y.L. Nair Hospital, Mumbai, IN
2 Department of Microbiology, Topiwala National Medical College & B.Y.L. Nair Hospital, Mumbai, 400008, IN
Source
The Indian Practitioner, Vol 68, No 1 (2015), Pagination: 44-45Abstract
No Abstract.
- Streptomycin Monoresistant Extrapulmonary Tuberculosis in an Immunocompetent Healthcare Worker-A Case Report
Authors
1 Dept. of Microbiology, TNMC & BYL Nair Ch. Hosp., Mumbai Central, Mumbai-400008, IN
Source
The Indian Practitioner, Vol 67, No 9 (2014), Pagination: 566-570Abstract
Tuberculosis (TB) is a major health problem in India and extrapulmonary tuberculosis (EPTB) comprises 20% of all cases of TB. EPTB is more common in HIV positive individuals and immunocompromised patients. In immunocompetent adults it has been observed that EPTB constitutes 15%-20% of all cases of tuberculosis. The emergence of strains of Mycobacterium tuberculosis that are resistant to antimycobacterial agents although not a new problem has recently received increased attention owing largely to outbreaks of drug resistant tuberculosis in HIV infected people. The true global magnitude of drug resistant tuberculosis is not well described. Here we report a case of streptomycin monoresistant mediastinal tuberculosis in a 29 year old Medical student. We wish to report this case because of rarity of streptomycin monoresistant in a case of extrapulmonary tuberculosis in an immunocompetent medical student.Keywords
Streptomycin monoresistant, Extrapulmonary Tuberculosis.- Antimicrobial Resistance in Salmonella Experience of an Infectious Diseases Hospital in Mumbai, India
Authors
1 Room No. 304A, 3rd Floor, College Building, Dept. of Microbiology, Topiwala National Medical College and BYL Nair Ch. Hospital, Dr. A.L. Nair Road, Mumbai-400 008, IN
2 Department of Microbiology, T.N.Medical College & BYL Nair Ch. Hospital, Mumbai, IN
3 Department of Microbiology, Kasturba Hospital for Infectious Diseases, Mumbai, IN
4 Kasturba Hospital for Infectious Diseases, Mumbai, IN
Source
The Indian Practitioner, Vol 67, No 4 (2014), Pagination: 224-228Abstract
Background: Enteric fever (EF) remains an important public health problem, particularly in the developing countries. The last two decades have witnessed the emergence of multidrug- resistant (MDR) salmonella strains.Objectives: To detect antimicrobial resistance among salmonella isolates from EF cases and to determine the minimum inhibitory concentration (MIC) of ciprofloxacin in nalidixic acid (NA) sensitive/ resistant strains of salmonellae.
Material and Methods: 890 clinically suspected cases of EF were studied at an Infectious diseases hospital in Mumbai between January June 2006. Clot culture was done in bile broth using conventional techniques. Typical nonlactose fermenting colonies on MacConkey agar were selected and identified by Gram's stain and conventional biochemical tests. Salmonella species were further confirmed by slide agglutination test using polyvalent and factor sera (Denka seiken, Japan). Antimicrobial susceptibility testing was done by Kirby-Bauer disk diffusion method in accordance with the CLSI guidelines and interpretative criteria.
Results: Fifty salmonella isolates from 890 suspected cases of EF (5.6%), comprised of Salmonella typhi (28;56%) and Salmonella paratyphi A (22;44%). All the isolates were sensitive to ciprofloxacin. The 49 (98%) NA-resistant strains had raised MIC of ciprofloxacin. Analysis of 5-year data revealed increasing resistance to NA, increasing sensitivity to chloramphenicol with ciprofloxacin sensitivity constant at 100%.
Conclusions: Recognition of a distinct subset of EF salmonellae having low-level resistance to ciprofloxacin is important for proper patient management in these cases. Vigilance for the emergence of ciprofloxacin or ceftriaxone-resistant strains is recommended.